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Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels
BACKGROUND: KCNH family of potassium channels is responsible for diverse physiological functions ranging from the regulation of neuronal excitability and cardiac contraction to the regulation of cancer progression. KCNH channels contain a Per-Arn-Sim (PAS) domain in their N-terminal and cyclic nucle...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637479/ https://www.ncbi.nlm.nih.gov/pubmed/31315662 http://dx.doi.org/10.1186/s40360-019-0324-8 |