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Sirtuin1 activator SRT2183 suppresses glioma cell growth involving activation of endoplasmic reticulum stress pathway

BACKGROUND: Glioblastoma (GBM) is an extremely deadly form of brain cancer with limited treatment options and thus novel therapeutic modalities are necessary. Histone deacetylase inhibitors (HDACi) have demonstrated clinical and preclinical activities against GBM. (Silent mating type information reg...

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Detalles Bibliográficos
Autores principales:	Ye, Tian, Wei, Liwen, Shi, Ji, Jiang, Ke, Xu, Huizhe, Hu, Lulu, Kong, Lingkai, Zhang, Ye, Meng, Songshu, Piao, Haozhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637499/ https://www.ncbi.nlm.nih.gov/pubmed/31319814 http://dx.doi.org/10.1186/s12885-019-5852-5

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