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A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis

BACKGROUND: IDO1 (Indoleamine 2,3-dioxygenase 1) inhibits host anti-tumor immune response by exhausting tryptophan in tumor microenvironment, but the pathogenic mechanisms of IDO1 in gastric cancer (GC) cells need to be further explored. METHODS: The aim of this study was to use CCLE (Cancer Cell Li...

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Detalles Bibliográficos
Autores principales:	Xiang, Zhen, Li, Jun, Song, Shuzheng, Wang, Jiexuan, Cai, Wei, Hu, Wenjun, Ji, Jun, Zhu, Zhenggang, Zang, Lu, Yan, Ranlin, Yu, Yingyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637527/ https://www.ncbi.nlm.nih.gov/pubmed/31315643 http://dx.doi.org/10.1186/s13046-019-1318-5

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