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Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia
Changes in cell metabolism and metabolic adaptation are hallmark features of many cancers, including leukemia, that support biological processes involved into tumor initiation, growth, and response to therapeutics. The discovery of mutations in key metabolic enzymes has highlighted the importance of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637566/ https://www.ncbi.nlm.nih.gov/pubmed/31319822 http://dx.doi.org/10.1186/s12915-019-0670-4 |