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Dynamic Compressive Loading Improves Cartilage Repair in an In Vitro Model of Microfracture: Comparison of 2 Mechanical Loading Regimens on Simulated Microfracture Based on Fibrin Gel Scaffolds Encapsulating Connective Tissue Progenitor Cells
BACKGROUND: Microfracture of focal chondral defects often produces fibrocartilage, which inconsistently integrates with the surrounding native tissue and possesses inferior mechanical properties compared with hyaline cartilage. Mechanical loading modulates cartilage during development, but it remain...
Autores principales: | Iseki, Tomoya, Rothrauff, Benjamin B., Kihara, Shinsuke, Sasaki, Hiroshi, Yoshiya, Shinichi, Fu, Freddie H., Tuan, Rocky S., Gottardi, Riccardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637720/ https://www.ncbi.nlm.nih.gov/pubmed/31307219 http://dx.doi.org/10.1177/0363546519855645 |
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