Routine Cerebrospinal Fluid Cytology Reveals Unique Inclusions in Macrophages During Treatment With Nusinersen

Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder characterized by degeneration of spinal motor neurons leading to muscular weakness. The antisense oligonucleotide nusinersen was approved for the treatment of patients with 5q-associated SMA. Treatment mus...

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Detalles Bibliográficos
Autores principales: Gingele, Stefan, Hümmert, Martin W., Alvermann, Sascha, Jendretzky, Konstantin F., Bönig, Lena, Brieskorn, Marina, Schwenkenbecher, Philipp, Sühs, Kurt-Wolfram, Müschen, Lars H., Osmanovic, Alma, Schreiber-Katz, Olivia, Stangel, Martin, Petri, Susanne, Skripuletz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637748/
https://www.ncbi.nlm.nih.gov/pubmed/31354609
http://dx.doi.org/10.3389/fneur.2019.00735

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