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Docking, Interaction Fingerprint, and Three-Dimensional Quantitative Structure–Activity Relationship (3D-QSAR) of Sigma1 Receptor Ligands, Analogs of the Neuroprotective Agent RC-33

The human Sigma1 receptor (S1R), which has been identified as a target with an important role in neuropsychological disorders, was first crystallized 3 years ago. Since S1R structure has no relation with another previous crystallized structures, the presence of the new crystal is an important hallma...

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Detalles Bibliográficos
Autores principales:	Velázquez-Libera, José Luis, Rossino, Giacomo, Navarro-Retamal, Carlos, Collina, Simona, Caballero, Julio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637851/ https://www.ncbi.nlm.nih.gov/pubmed/31355187 http://dx.doi.org/10.3389/fchem.2019.00496

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