Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis

The Amyloid Precursor Protein (APP) and Contactin (CNTN) families of cell-surface proteins have been intensively studied in the context of neural development and neuropsychiatric diseases. Earlier studies demonstrated both genetic and biochemical interactions between the extracellular domains of APP...

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Detalles Bibliográficos
Autores principales: Peng, Xi, Williams, John, Smallwood, Philip M., Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638891/
https://www.ncbi.nlm.nih.gov/pubmed/31318883
http://dx.doi.org/10.1371/journal.pone.0219384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638891/
https://www.ncbi.nlm.nih.gov/pubmed/31318883
http://dx.doi.org/10.1371/journal.pone.0219384

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