Improvement in detecting cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance using next generation sequencing

OBJETIVES: The aim of this study was to identify CMV drug resistance mutations (DRM) in solid organ transplant (SOT) recipients with suspected resistance comparing next-generation sequencing (NGS) with Sanger sequencing and assessing risk factors and the clinical impact of resistance. METHODS: Using...

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Detalles Bibliográficos
Autores principales: López-Aladid, Rubén, Guiu, Alba, Mosquera, Maria Mar, López-Medrano, Francisco, Cofán, Frederic, Linares, Laura, Torre-Cisneros, Julián, Vidal, Elisa, Moreno, Asunción, Aguado, Jose María, Cordero, Elisa, Martin-Gandul, Cecilia, Carratalá, Jordi, Sabé, Nuria, Niubó, Jordi, Cervera, Carlos, Capón, Alicia, Cervilla, Anna, Santos, Marta, Bodro, Marta, Muñoz, Patricia, Fariñas, Maria Carmen, Antón, Andrés, Aranzamendi, Maitane, Montejo, Miguel, Pérez-Romero, Pilar, Len, Oscar, Marcos, Maria Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638921/
https://www.ncbi.nlm.nih.gov/pubmed/31318908
http://dx.doi.org/10.1371/journal.pone.0219701

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