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Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity

Natural variation separates Epstein-Barr virus (EBV) into type 1 and type 2 strains. Type 2 EBV is less transforming in vitro due to sequence differences in the EBV transcription factor EBNA2. This correlates with reduced activation of the EBV oncogene LMP1 and some cell genes. Transcriptional activ...

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Detalles Bibliográficos
Autores principales:	Ponnusamy, Rajesh, Khatri, Ritika, Correia, Paulo B., Wood, C. David, Mancini, Erika J., Farrell, Paul J., West, Michelle J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6638984/ https://www.ncbi.nlm.nih.gov/pubmed/31283782 http://dx.doi.org/10.1371/journal.ppat.1007458

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