Cargando…
NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content
In mature neurons, postsynaptic N-methyl-D-aspartate receptors (NMDARs) are segregated into two populations, synaptic and extrasynaptic, which differ in localization, function, and associated intracellular cascades. These two pools are connected via lateral diffusion, and receptor exchange between t...
Autores principales: | Chiu, Andrew M., Wang, Jiejie, Fiske, Michael P., Hubalkova, Pavla, Barse, Levi, Gray, John A., Sanz-Clemente, Antonio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639021/ https://www.ncbi.nlm.nih.gov/pubmed/31291571 http://dx.doi.org/10.1016/j.celrep.2019.06.030 |
Ejemplares similares
-
GluN2B and GluN2D NMDARs dominate synaptic responses in the adult spinal cord
por: Hildebrand, Michael E., et al.
Publicado: (2014) -
The C-terminus of NMDAR GluN1-1a Subunit Translocates to Nucleus and Regulates Synaptic Function
por: Zhou, Liang, et al.
Publicado: (2018) -
GluN2B-containing NMDARs in the mammalian brain: pharmacology, physiology, and pathology
por: Ge, Yang, et al.
Publicado: (2023) -
GluN2B and GluN2A-containing NMDAR are differentially involved in extinction memory destabilization and restabilization during reconsolidation
por: Radiske, Andressa, et al.
Publicado: (2021) -
GluN2A and GluN2B N-Methyl-D-Aspartate Receptor (NMDARs) Subunits: Their Roles and Therapeutic Antagonists in Neurological Diseases
por: Ladagu, Amany Digal, et al.
Publicado: (2023)