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Overexpression of PRDM5 promotes acute myeloid leukemia cell proliferation and migration by activating the JNK pathway

PRDM family proteins are dysregulated in many human diseases, especially hematological malignancies and solid cancers, and share a unique N‐terminal PR domain followed by zinc fingers toward the C terminus. With a high frequency of DNA promoter hypermethylation, PRDM5 is primarily considered as a tu...

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Detalles Bibliográficos
Autores principales:	Zhou, Pan, Chen, Xing, Li, Mengke, Sun, Xiaolu, Tan, Jiaqi, Wang, Xiaomin, Chu, Yajing, Zhang, Yicheng, Cheng, Tao, Zhou, Jianfeng, Wang, Gaoxiang, Yuan, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639193/ https://www.ncbi.nlm.nih.gov/pubmed/31119897 http://dx.doi.org/10.1002/cam4.2261

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