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CD26 expression is attenuated by TGF‐β and SDF‐1 autocrine signaling on stromal myofibroblasts in human breast cancers

Human breast carcinoma‐associated fibroblasts (CAFs) increasingly acquire both transforming growth factor‐β (TGF‐β) and stromal cell‐derived factor‐1 (SDF‐1) signaling in an autocrine fashion during tumor progression. Such signaling mediates activated myofibroblastic and tumor‐promoting properties i...

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Detalles Bibliográficos
Autores principales: Mezawa, Yoshihiro, Daigo, Yataro, Takano, Atsushi, Miyagi, Yohei, Yokose, Tomoyuki, Yamashita, Toshinari, Morimoto, Chikao, Hino, Okio, Orimo, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639198/
https://www.ncbi.nlm.nih.gov/pubmed/31140748
http://dx.doi.org/10.1002/cam4.2249