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Infectious Virus Persists in CD4(+) T Cells and Macrophages in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques
Understanding the cellular and anatomical sites of latent virus that contribute to human immunodeficiency virus (HIV) rebound is essential for eradication. In HIV-positive patients, CD4(+) T lymphocytes comprise a well-defined functional latent reservoir, defined as cells containing transcriptionall...
Autores principales: | Abreu, Celina M., Veenhuis, Rebecca T., Avalos, Claudia R., Graham, Shelby, Queen, Suzanne E., Shirk, Erin N., Bullock, Brandon T., Li, Ming, Metcalf Pate, Kelly A., Beck, Sarah E., Mangus, Lisa M., Mankowski, Joseph L., Clements, Janice E., Gama, Lucio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639293/ https://www.ncbi.nlm.nih.gov/pubmed/31118264 http://dx.doi.org/10.1128/JVI.00065-19 |
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