Cargando…

Bypassing pan-enterovirus host factor PLA2G16

Enteroviruses are a major cause of human disease. Adipose-specific phospholipase A2 (PLA2G16) was recently identified as a pan-enterovirus host factor and potential drug target. In this study, we identify a possible mechanism of PLA2G16 evasion by employing a dual glycan receptor-binding enterovirus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baggen, Jim, Liu, Yue, Lyoo, Heyrhyoung, van Vliet, Arno L. W., Wahedi, Maryam, de Bruin, Jost W., Roberts, Richard W., Overduin, Pieter, Meijer, Adam, Rossmann, Michael G., Thibaut, Hendrik Jan, van Kuppeveld, Frank J. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639302/ https://www.ncbi.nlm.nih.gov/pubmed/31320648 http://dx.doi.org/10.1038/s41467-019-11256-z

Ejemplares similares

Proteolytic Activities of Enterovirus 2A Do Not Depend on Its Interaction with SETD3
por: Yang, Xiaoyao, et al.
Publicado: (2022)

Sialic acid-dependent cell entry of human enterovirus D68
por: Liu, Yue, et al.
Publicado: (2015)

Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus
por: Baggen, Jim, et al.
Publicado: (2019)

Direct-acting antivirals and host-targeting strategies to combat enterovirus infections
por: Bauer, Lisa, et al.
Publicado: (2017)

Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence
por: Sun, Liang, et al.
Publicado: (2019)

ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB
por: Lyoo, Heyrhyoung, et al.
Publicado: (2019)

Escaping Host Factor PI4KB Inhibition: Enterovirus Genomic RNA Replication in the Absence of Replication Organelles
por: Melia, Charlotte E., et al.
Publicado: (2017)

Enterovirus D-68 Infection of Primary Rat Cortical Neurons: Entry, Replication, and Functional Consequences
por: Poelaert, Katrien C. K., et al.
Publicado: (2023)

Replication and Inhibitors of Enteroviruses and Parechoviruses
por: van der Linden, Lonneke, et al.
Publicado: (2015)

Binding of Glutathione to Enterovirus Capsids Is Essential for Virion Morphogenesis
por: Thibaut, Hendrik Jan, et al.
Publicado: (2014)

Cholesterol: fa(s)t-food for enterovirus genome replication
por: Strating, Jeroen R.P., et al.
Publicado: (2013)

The cellular receptor for enterovirus 71
por: Liu, Yue, et al.
Publicado: (2014)

Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites
por: Horova, Vladimira, et al.
Publicado: (2019)

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein
por: Strating, Jeroen R.P.M., et al.
Publicado: (2015)

Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex
por: Hurdiss, Daniel L., et al.
Publicado: (2022)

Pan-viral serology implicates enteroviruses in acute flaccid myelitis
por: Schubert, Ryan D., et al.
Publicado: (2019)

Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C
por: Ulferts, Rachel, et al.
Publicado: (2016)

The Transformation of Enterovirus Replication Structures: a Three-Dimensional Study of Single- and Double-Membrane Compartments
por: Limpens, Ronald W. A. L., et al.
Publicado: (2011)

Origins of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy
por: Melia, Charlotte E., et al.
Publicado: (2019)

Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding Protein
por: Dorobantu, Cristina M., et al.
Publicado: (2016)

Enhanced Enterovirus D68 Replication in Neuroblastoma Cells Is Associated with a Cell Culture-Adaptive Amino Acid Substitution in VP1
por: Sooksawasdi Na Ayudhya, Syriam, et al.
Publicado: (2020)

Phagocytosis of Enterovirus-Infected Pancreatic β-Cells Triggers Innate Immune Responses in Human Dendritic Cells
por: Schulte, Barbara M., et al.
Publicado: (2010)

Enterovirus D68 Infection in Human Primary Airway and Brain Organoids: No Additional Role for Heparan Sulfate Binding for Neurotropism
por: Sridhar, Adithya, et al.
Publicado: (2022)

Cytokine and Chemokine Production by Human Pancreatic Islets Upon Enterovirus Infection
por: Schulte, Barbara M., et al.
Publicado: (2012)

Differential Susceptibility and Response of Primary Human Myeloid BDCA1(+) Dendritic Cells to Infection with Different Enteroviruses
por: Schulte, Barbara M., et al.
Publicado: (2013)

Illuminating the Sites of Enterovirus Replication in Living Cells by Using a Split-GFP-Tagged Viral Protein
por: van der Schaar, H. M., et al.
Publicado: (2016)

Pla2g2a Attenuates Colon Tumorigenesis in Azoxymethane-Treated C57BL/6 Mice; Expression Studies Reveal Pla2g2a Target Genes and Pathways
por: Fijneman, Remond J. A., et al.
Publicado: (2009)

Enterovirus-Infected β-Cells Induce Distinct Response Patterns in BDCA1(+) and BDCA3(+) Human Dendritic Cells
por: Schulte, Barbara M., et al.
Publicado: (2015)

Erratum for Sooksawasdi Na Ayudhya et al., “Enhanced Enterovirus D68 Replication in Neuroblastoma Cells Is Associated with a Cell Culture-Adaptive Amino Acid Substitution in VP1”
por: Sooksawasdi Na Ayudhya, Syriam, et al.
Publicado: (2020)

Gastric Bypass and Abdominal Pain: Think of Petersen Hernia
por: de Bakker, J. K., et al.
Publicado: (2012)

A One-Step, Triplex, Real-Time RT-PCR Assay for the Simultaneous Detection of Enterovirus 71, Coxsackie A16 and Pan-Enterovirus in a Single Tube
por: Zhang, Shiyin, et al.
Publicado: (2014)

Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner
por: Bauer, Lisa, et al.
Publicado: (2019)

Enterovirus and parechovirus infection in children: a brief overview
por: de Crom, S. C. M., et al.
Publicado: (2016)

Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine
por: Klooster, Jean Paul ten, et al.
Publicado: (2021)

Translation and Replication Dynamics of Single RNA Viruses
por: Boersma, Sanne, et al.
Publicado: (2020)

Smart PEG-Block-PLA/PLA Nanosystems: Impact of the Characteristics of the Polymer Blend on the Redox Responsiveness
por: Van Gheluwe, Louise, et al.
Publicado: (2023)

Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
por: Giansanti, Piero, et al.
Publicado: (2020)

Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation
por: Dirmeier, Simon, et al.
Publicado: (2020)

Validation study of 3D-printed anatomical models using 2 PLA printers for preoperative planning in trauma surgery, a human cadaver study
por: Brouwers, Lars, et al.
Publicado: (2018)

Three-Step Synthesis of a Redox-Responsive Blend of PEG–block–PLA and PLA and Application to the Nanoencapsulation of Retinol
por: Van Gheluwe, Louise, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_br3jgn0dofpj2ddto4o724n6l3