Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells

While the immune cell adaptor protein SKAP1 mediates LFA-1 activation induced by antigen-receptor (TCR/CD3) ligation on T-cells, it is unclear whether the adaptor interacts with other mediators of T-cell function. In this context, the serine/threonine kinase, polo-like kinase (PLK1) regulates multip...

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Detalles Bibliográficos
Autores principales: Raab, Monika, Strebhardt, Klaus, Rudd, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639320/
https://www.ncbi.nlm.nih.gov/pubmed/31320682
http://dx.doi.org/10.1038/s41598-019-45627-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639320/
https://www.ncbi.nlm.nih.gov/pubmed/31320682
http://dx.doi.org/10.1038/s41598-019-45627-9

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