Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets

Knowledge of key drivers and therapeutic targets in mucosal melanoma is limited due to the paucity of comprehensive mutation data on this rare tumor type. To better understand the genomic landscape of mucosal melanoma, here we describe whole genome sequencing analysis of 67 tumors and validation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Newell, Felicity, Kong, Yan, Wilmott, James S., Johansson, Peter A., Ferguson, Peter M., Cui, Chuanliang, Li, Zhongwu, Kazakoff, Stephen H., Burke, Hazel, Dodds, Tristan J., Patch, Ann-Marie, Nones, Katia, Tembe, Varsha, Shang, Ping, van der Weyden, Louise, Wong, Kim, Holmes, Oliver, Lo, Serigne, Leonard, Conrad, Wood, Scott, Xu, Qinying, Rawson, Robert V., Mukhopadhyay, Pamela, Dummer, Reinhard, Levesque, Mitchell P., Jönsson, Göran, Wang, Xuan, Yeh, Iwei, Wu, Hong, Joseph, Nancy, Bastian, Boris C., Long, Georgina V., Spillane, Andrew J., Shannon, Kerwin F., Thompson, John F., Saw, Robyn P. M., Adams, David J., Si, Lu, Pearson, John V., Hayward, Nicholas K., Waddell, Nicola, Mann, Graham J., Guo, Jun, Scolyer, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639323/
https://www.ncbi.nlm.nih.gov/pubmed/31320640
http://dx.doi.org/10.1038/s41467-019-11107-x

Ejemplares similares

Ejemplares similares