Cargando…
Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells
Formation of new blood vessels by differentiated endothelial tip cells, stalk cells, and phalanx cells during angiogenesis is an energy-demanding process. How these specialized endothelial cell phenotypes generate their energy, and whether there are differences between these phenotypes, is unknown....
Autores principales: | Yetkin-Arik, B., Vogels, I. M. C., Neyazi, N., van Duinen, V., Houtkooper, R. H., van Noorden, C. J. F., Klaassen, I., Schlingemann, R. O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639367/ https://www.ncbi.nlm.nih.gov/pubmed/31320669 http://dx.doi.org/10.1038/s41598-019-46503-2 |
Ejemplares similares
-
The role of glycolysis and mitochondrial respiration in the formation and functioning of endothelial tip cells during angiogenesis
por: Yetkin-Arik, Bahar, et al.
Publicado: (2019) -
CD34 marks angiogenic tip cells in human vascular endothelial cell cultures
por: Siemerink, Martin J., et al.
Publicado: (2012) -
IGF2 and IGF1R identified as novel tip cell genes in primary microvascular endothelial cell monolayers
por: Dallinga, Marchien G., et al.
Publicado: (2018) -
Endothelial Tip Cells in Ocular Angiogenesis: Potential Target for Anti-Angiogenesis Therapy
por: Siemerink, Martin J., et al.
Publicado: (2013) -
The Role of Heparan Sulfate and Neuropilin 2 in VEGFA Signaling in Human Endothelial Tip Cells and Non-Tip Cells during Angiogenesis In Vitro
por: Dallinga, Marchien G., et al.
Publicado: (2021)