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F-box protein FBXO30 mediates retinoic acid receptor γ ubiquitination and regulates BMP signaling in neural tube defects

Retinoic acid (RA), an active derivative of vitamin A, is critical for the neural system development. During the neural development, the RA/RA receptor (RAR) pathway suppresses BMP signaling-mediated proliferation and differentiation of neural progenitor cells. However, how the stability of RAR is r...

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Detalles Bibliográficos
Autores principales: Cheng, Xiyue, Pei, Pei, Yu, Juan, Zhang, Qin, Li, Dan, Xie, Xiaolu, Wu, Jianxin, Wang, Shan, Zhang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639381/
https://www.ncbi.nlm.nih.gov/pubmed/31320612
http://dx.doi.org/10.1038/s41419-019-1783-y

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