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F-box protein FBXO30 mediates retinoic acid receptor γ ubiquitination and regulates BMP signaling in neural tube defects
Retinoic acid (RA), an active derivative of vitamin A, is critical for the neural system development. During the neural development, the RA/RA receptor (RAR) pathway suppresses BMP signaling-mediated proliferation and differentiation of neural progenitor cells. However, how the stability of RAR is r...
Autores principales: | Cheng, Xiyue, Pei, Pei, Yu, Juan, Zhang, Qin, Li, Dan, Xie, Xiaolu, Wu, Jianxin, Wang, Shan, Zhang, Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639381/ https://www.ncbi.nlm.nih.gov/pubmed/31320612 http://dx.doi.org/10.1038/s41419-019-1783-y |
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