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Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment
The process of vascular remodeling is associated with increased hypoxia. However, the contribution of hypoxia-inducible factor 1α (HIF1α), the key transcription factor mediating cellular hypoxic responses, to vascular remodeling is established, but not completely understood. In the angiotensin II (A...
Autores principales: | Qi, Dan, Wei, Ming, Jiao, Shiyu, Song, Yanting, Wang, Xia, Xie, Guomin, Taranto, Joseph, Liu, Ye, Duan, Yan, Yu, Baoqi, Li, Huihua, Shah, Yatrik M., Xu, Qingbo, Du, Jie, Gonzalez, Frank J., Qu, Aijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639417/ https://www.ncbi.nlm.nih.gov/pubmed/31320613 http://dx.doi.org/10.1038/s41419-019-1757-0 |
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