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Heterogeneous nuclear ribonucleoprotein L facilitates recruitment of 53BP1 and BRCA1 at the DNA break sites induced by oxaliplatin in colorectal cancer

Although oxaliplatin is an effective chemotherapeutic drug for treatment of colorectal cancer (CRC), tumor cells can develop mechanisms to evade oxaliplatin-induced cell death and show high tolerance and acquired resistance to this drug. Heterogeneous nuclear ribonucleoprotein L (hnRNP L) has been p...

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Detalles Bibliográficos
Autores principales:	Hu, Wenjun, Lei, Linping, Xie, Xuqin, Huang, Libin, Cui, Qian, Dang, Tang, Liu, Gang Logan, Li, Yuan, Sun, Xiaofeng, Zhou, Zongguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639419/ https://www.ncbi.nlm.nih.gov/pubmed/31320608 http://dx.doi.org/10.1038/s41419-019-1784-x

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