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Association of the canine ATP7A and ATP7B with hepatic copper accumulation in Dobermann dogs

BACKGROUND: Hepatic copper accumulation causes chronic hepatitis in dogs. Mutations in the copper transporters ATP7A and ATP7B were, respectively, associated with attenuation and enhancement of hepatic copper concentrations in Labrador Retrievers. There is a predisposition of Dobermanns to hepatitis...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyan, Mandigers, Paul J. J., Watson, Adrian L., van den Ingh, Ted S. G. A. M., Leegwater, Peter A. J., Fieten, Hille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639496/
https://www.ncbi.nlm.nih.gov/pubmed/31254371
http://dx.doi.org/10.1111/jvim.15536