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Transplant-Amenable Hepatocellular Carcinoma in a Fontan Patient

The Fontan circulation alters a patient's physiology and imparts long-term risks related to chronically elevated systemic venous pressure. An increasing number of patients with Fontan physiology are surviving into adulthood and are at risk of hepatic sequalae. The ideal timeline and method of h...

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Autores principales: Rutledge, Brian Patrick, Devara, Anupama, Benjaram, Sindhuri, Judd, Stephanie, Ehrinpreis, Murray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639574/
https://www.ncbi.nlm.nih.gov/pubmed/31341459
http://dx.doi.org/10.1159/000501198
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author Rutledge, Brian Patrick
Devara, Anupama
Benjaram, Sindhuri
Judd, Stephanie
Ehrinpreis, Murray
author_facet Rutledge, Brian Patrick
Devara, Anupama
Benjaram, Sindhuri
Judd, Stephanie
Ehrinpreis, Murray
author_sort Rutledge, Brian Patrick
collection PubMed
description The Fontan circulation alters a patient's physiology and imparts long-term risks related to chronically elevated systemic venous pressure. An increasing number of patients with Fontan physiology are surviving into adulthood and are at risk of hepatic sequalae. The ideal timeline and method of hepatic surveillance in the Fontan population remains to be defined. In this case, the patient was diagnosed with hepatocellular carcinoma more than 20 years after undergoing the Fontan procedure and was a candidate for combined heart-liver transplant. That her disease progressed prior to organ availability supports the argument for hepatic surveillance in this population.
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spelling pubmed-66395742019-07-24 Transplant-Amenable Hepatocellular Carcinoma in a Fontan Patient Rutledge, Brian Patrick Devara, Anupama Benjaram, Sindhuri Judd, Stephanie Ehrinpreis, Murray Case Rep Gastroenterol Single Case The Fontan circulation alters a patient's physiology and imparts long-term risks related to chronically elevated systemic venous pressure. An increasing number of patients with Fontan physiology are surviving into adulthood and are at risk of hepatic sequalae. The ideal timeline and method of hepatic surveillance in the Fontan population remains to be defined. In this case, the patient was diagnosed with hepatocellular carcinoma more than 20 years after undergoing the Fontan procedure and was a candidate for combined heart-liver transplant. That her disease progressed prior to organ availability supports the argument for hepatic surveillance in this population. S. Karger AG 2019-06-26 /pmc/articles/PMC6639574/ /pubmed/31341459 http://dx.doi.org/10.1159/000501198 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Rutledge, Brian Patrick
Devara, Anupama
Benjaram, Sindhuri
Judd, Stephanie
Ehrinpreis, Murray
Transplant-Amenable Hepatocellular Carcinoma in a Fontan Patient
title Transplant-Amenable Hepatocellular Carcinoma in a Fontan Patient
title_full Transplant-Amenable Hepatocellular Carcinoma in a Fontan Patient
title_fullStr Transplant-Amenable Hepatocellular Carcinoma in a Fontan Patient
title_full_unstemmed Transplant-Amenable Hepatocellular Carcinoma in a Fontan Patient
title_short Transplant-Amenable Hepatocellular Carcinoma in a Fontan Patient
title_sort transplant-amenable hepatocellular carcinoma in a fontan patient
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639574/
https://www.ncbi.nlm.nih.gov/pubmed/31341459
http://dx.doi.org/10.1159/000501198
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