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Comparison of DNA Methylation in Vibrio vulnificus Cells Grown in Human Serum with Those Grown in Seawater

The chromosomal methylation statuses of the highly virulent Vibrio vulnificus strain CMCP6 grown in human serum and in seawater are compared here. Growth in seawater resulted in ∼4 times as much methylation as that in human serum, primarily N(4)-methylcytosines.

Detalles Bibliográficos
Autores principales: Conrad, James W., Harwood, Valerie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639608/
https://www.ncbi.nlm.nih.gov/pubmed/31320429
http://dx.doi.org/10.1128/MRA.00419-19
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author Conrad, James W.
Harwood, Valerie J.
author_facet Conrad, James W.
Harwood, Valerie J.
author_sort Conrad, James W.
collection PubMed
description The chromosomal methylation statuses of the highly virulent Vibrio vulnificus strain CMCP6 grown in human serum and in seawater are compared here. Growth in seawater resulted in ∼4 times as much methylation as that in human serum, primarily N(4)-methylcytosines.
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spelling pubmed-66396082019-08-06 Comparison of DNA Methylation in Vibrio vulnificus Cells Grown in Human Serum with Those Grown in Seawater Conrad, James W. Harwood, Valerie J. Microbiol Resour Announc Genome Sequences The chromosomal methylation statuses of the highly virulent Vibrio vulnificus strain CMCP6 grown in human serum and in seawater are compared here. Growth in seawater resulted in ∼4 times as much methylation as that in human serum, primarily N(4)-methylcytosines. American Society for Microbiology 2019-07-18 /pmc/articles/PMC6639608/ /pubmed/31320429 http://dx.doi.org/10.1128/MRA.00419-19 Text en Copyright © 2019 Conrad and Harwood. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Genome Sequences
Conrad, James W.
Harwood, Valerie J.
Comparison of DNA Methylation in Vibrio vulnificus Cells Grown in Human Serum with Those Grown in Seawater
title Comparison of DNA Methylation in Vibrio vulnificus Cells Grown in Human Serum with Those Grown in Seawater
title_full Comparison of DNA Methylation in Vibrio vulnificus Cells Grown in Human Serum with Those Grown in Seawater
title_fullStr Comparison of DNA Methylation in Vibrio vulnificus Cells Grown in Human Serum with Those Grown in Seawater
title_full_unstemmed Comparison of DNA Methylation in Vibrio vulnificus Cells Grown in Human Serum with Those Grown in Seawater
title_short Comparison of DNA Methylation in Vibrio vulnificus Cells Grown in Human Serum with Those Grown in Seawater
title_sort comparison of dna methylation in vibrio vulnificus cells grown in human serum with those grown in seawater
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639608/
https://www.ncbi.nlm.nih.gov/pubmed/31320429
http://dx.doi.org/10.1128/MRA.00419-19
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