Cargando…

Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease

Nontypeable Haemophilus influenzae (NTHi) is a major bacterial cause of exacerbations in chronic obstructive pulmonary disease (COPD). Here, we report high-depth coverage transcriptome sequencing (RNA-seq) data from two NTHi strains, each encoding a different phase-variable methyltransferase. modA p...

Descripción completa

Detalles Bibliográficos
Autores principales: Atack, John M., Murphy, Timothy F., Pettigrew, Melinda M., Seib, Kate L., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639615/
https://www.ncbi.nlm.nih.gov/pubmed/31320413
http://dx.doi.org/10.1128/MRA.00526-19
_version_ 1783436497018421248
author Atack, John M.
Murphy, Timothy F.
Pettigrew, Melinda M.
Seib, Kate L.
Jennings, Michael P.
author_facet Atack, John M.
Murphy, Timothy F.
Pettigrew, Melinda M.
Seib, Kate L.
Jennings, Michael P.
author_sort Atack, John M.
collection PubMed
description Nontypeable Haemophilus influenzae (NTHi) is a major bacterial cause of exacerbations in chronic obstructive pulmonary disease (COPD). Here, we report high-depth coverage transcriptome sequencing (RNA-seq) data from two NTHi strains, each encoding a different phase-variable methyltransferase. modA phase variation results in gene expression differences. These data will serve as an important resource for future studies.
format Online
Article
Text
id pubmed-6639615
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher American Society for Microbiology
record_format MEDLINE/PubMed
spelling pubmed-66396152019-08-06 Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease Atack, John M. Murphy, Timothy F. Pettigrew, Melinda M. Seib, Kate L. Jennings, Michael P. Microbiol Resour Announc Omics Data Sets Nontypeable Haemophilus influenzae (NTHi) is a major bacterial cause of exacerbations in chronic obstructive pulmonary disease (COPD). Here, we report high-depth coverage transcriptome sequencing (RNA-seq) data from two NTHi strains, each encoding a different phase-variable methyltransferase. modA phase variation results in gene expression differences. These data will serve as an important resource for future studies. American Society for Microbiology 2019-07-18 /pmc/articles/PMC6639615/ /pubmed/31320413 http://dx.doi.org/10.1128/MRA.00526-19 Text en Copyright © 2019 Atack et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Omics Data Sets
Atack, John M.
Murphy, Timothy F.
Pettigrew, Melinda M.
Seib, Kate L.
Jennings, Michael P.
Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease
title Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease
title_full Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease
title_fullStr Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease
title_full_unstemmed Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease
title_short Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease
title_sort transcriptome sequencing data sets for determining gene expression changes mediated by phase-variable dna methyltransferases in nontypeable haemophilus influenzae strains isolated from patients with chronic obstructive pulmonary disease
topic Omics Data Sets
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639615/
https://www.ncbi.nlm.nih.gov/pubmed/31320413
http://dx.doi.org/10.1128/MRA.00526-19
work_keys_str_mv AT atackjohnm transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease
AT murphytimothyf transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease
AT pettigrewmelindam transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease
AT seibkatel transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease
AT jenningsmichaelp transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease