Cargando…
Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease
Nontypeable Haemophilus influenzae (NTHi) is a major bacterial cause of exacerbations in chronic obstructive pulmonary disease (COPD). Here, we report high-depth coverage transcriptome sequencing (RNA-seq) data from two NTHi strains, each encoding a different phase-variable methyltransferase. modA p...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639615/ https://www.ncbi.nlm.nih.gov/pubmed/31320413 http://dx.doi.org/10.1128/MRA.00526-19 |
_version_ | 1783436497018421248 |
---|---|
author | Atack, John M. Murphy, Timothy F. Pettigrew, Melinda M. Seib, Kate L. Jennings, Michael P. |
author_facet | Atack, John M. Murphy, Timothy F. Pettigrew, Melinda M. Seib, Kate L. Jennings, Michael P. |
author_sort | Atack, John M. |
collection | PubMed |
description | Nontypeable Haemophilus influenzae (NTHi) is a major bacterial cause of exacerbations in chronic obstructive pulmonary disease (COPD). Here, we report high-depth coverage transcriptome sequencing (RNA-seq) data from two NTHi strains, each encoding a different phase-variable methyltransferase. modA phase variation results in gene expression differences. These data will serve as an important resource for future studies. |
format | Online Article Text |
id | pubmed-6639615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-66396152019-08-06 Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease Atack, John M. Murphy, Timothy F. Pettigrew, Melinda M. Seib, Kate L. Jennings, Michael P. Microbiol Resour Announc Omics Data Sets Nontypeable Haemophilus influenzae (NTHi) is a major bacterial cause of exacerbations in chronic obstructive pulmonary disease (COPD). Here, we report high-depth coverage transcriptome sequencing (RNA-seq) data from two NTHi strains, each encoding a different phase-variable methyltransferase. modA phase variation results in gene expression differences. These data will serve as an important resource for future studies. American Society for Microbiology 2019-07-18 /pmc/articles/PMC6639615/ /pubmed/31320413 http://dx.doi.org/10.1128/MRA.00526-19 Text en Copyright © 2019 Atack et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Omics Data Sets Atack, John M. Murphy, Timothy F. Pettigrew, Melinda M. Seib, Kate L. Jennings, Michael P. Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease |
title | Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease |
title_full | Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease |
title_fullStr | Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease |
title_full_unstemmed | Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease |
title_short | Transcriptome Sequencing Data Sets for Determining Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae Strains Isolated from Patients with Chronic Obstructive Pulmonary Disease |
title_sort | transcriptome sequencing data sets for determining gene expression changes mediated by phase-variable dna methyltransferases in nontypeable haemophilus influenzae strains isolated from patients with chronic obstructive pulmonary disease |
topic | Omics Data Sets |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639615/ https://www.ncbi.nlm.nih.gov/pubmed/31320413 http://dx.doi.org/10.1128/MRA.00526-19 |
work_keys_str_mv | AT atackjohnm transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease AT murphytimothyf transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease AT pettigrewmelindam transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease AT seibkatel transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease AT jenningsmichaelp transcriptomesequencingdatasetsfordetermininggeneexpressionchangesmediatedbyphasevariablednamethyltransferasesinnontypeablehaemophilusinfluenzaestrainsisolatedfrompatientswithchronicobstructivepulmonarydisease |