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Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart

In the heart, primary microRNA-208b (pri-miR-208b) and Myheart (Mhrt) are long non-coding RNAs (lncRNAs) encoded by the cardiac myosin heavy chain genes. Although preclinical studies have shown that lncRNAs regulate gene expression and are protective for pathological hypertrophy, the mechanism under...

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Detalles Bibliográficos
Autores principales:	K.N., Harikrishnan, Okabe, Jun, Mathiyalagan, Prabhu, Khan, Abdul Waheed, Jadaan, Sameer A., Sarila, Gulcan, Ziemann, Mark, Khurana, Ishant, Maxwell, Scott S., Du, Xiao-Jun, El-Osta, Assam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639684/ https://www.ncbi.nlm.nih.gov/pubmed/31323475 http://dx.doi.org/10.1016/j.isci.2019.06.031

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