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Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia

INTRODUCTION: WHO recommends assisted partner notification (APN) for people living with HIV (PLHIV). These services have not been widely scaled in Central Asia. We describe the results from an APN intervention implemented within a programme focused on PLHIV and people who inject drugs in Kazakhstan,...

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Autores principales: Little, Kristen M, Kan, Maxim, Samoylova, Olga, Rsaldinova, Altynai, Saliev, Daniyar, Ishokov, Faridun, Gray, Robert, Hasen, Nina S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639697/
https://www.ncbi.nlm.nih.gov/pubmed/31321890
http://dx.doi.org/10.1002/jia2.25313
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author Little, Kristen M
Kan, Maxim
Samoylova, Olga
Rsaldinova, Altynai
Saliev, Daniyar
Ishokov, Faridun
Gray, Robert
Hasen, Nina S
author_facet Little, Kristen M
Kan, Maxim
Samoylova, Olga
Rsaldinova, Altynai
Saliev, Daniyar
Ishokov, Faridun
Gray, Robert
Hasen, Nina S
author_sort Little, Kristen M
collection PubMed
description INTRODUCTION: WHO recommends assisted partner notification (APN) for people living with HIV (PLHIV). These services have not been widely scaled in Central Asia. We describe the results from an APN intervention implemented within a programme focused on PLHIV and people who inject drugs in Kazakhstan, the Kyrgyz Republic and Tajikistan. METHODS: Routine data from index cases and their partners were analysed from equal‐length periods before and after APN launch. Prior to APN index cases could recruit partners using passive referral, and under APN, had their choice of passive referral or APN (provider, contract or dual‐referral). We compared the demographic characteristics of index cases and their sexual/injecting partners from the pre‐APN and APN periods, described the number/proportion of HIV cases found (positivity rate) and evaluated predictors of HIV infection among partners using logistic regression. RESULTS: Under APN 2676 PLHIV served as index cases and recruited 3735 partners for testing, compared to 4418 index cases and 2240 partners during the pre‐APN period. A total of 322 (8.6%) partners were rapid test positive during APN versus 161 (7.2%, p = 0.048) before APN. Women represented 38% of APN index cases (vs. 42% pre‐APN), 52% of partners tested (vs. 50% pre‐APN) and 56% of all PLHIV identified (vs. 63% pre‐APN). Compared to the pre‐APN period, the number of partners tested per index case recruited increased (0.5 to 1.4, p < 0.001) and the number of index cases needed to find one HIV‐positive partner decreased significantly (27.4 to 8.3, p < 0.001) under APN. CONCLUSIONS: APN was feasibly integrated within a people who inject drugs and PLHIV‐focused HIV programme, and was acceptable to high‐risk populations in Central Asia. Under APN, large numbers of sexual and injecting partners of PLHIV – including women and non‐marital partners – were tested while maintaining high positivity rates. Relative to the pre‐APN period, APN approximately tripled the number of partners recruited per index case and reduced the number of index cases needed to find a positive partner by >3 times.
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spelling pubmed-66396972019-07-29 Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia Little, Kristen M Kan, Maxim Samoylova, Olga Rsaldinova, Altynai Saliev, Daniyar Ishokov, Faridun Gray, Robert Hasen, Nina S J Int AIDS Soc Research Article INTRODUCTION: WHO recommends assisted partner notification (APN) for people living with HIV (PLHIV). These services have not been widely scaled in Central Asia. We describe the results from an APN intervention implemented within a programme focused on PLHIV and people who inject drugs in Kazakhstan, the Kyrgyz Republic and Tajikistan. METHODS: Routine data from index cases and their partners were analysed from equal‐length periods before and after APN launch. Prior to APN index cases could recruit partners using passive referral, and under APN, had their choice of passive referral or APN (provider, contract or dual‐referral). We compared the demographic characteristics of index cases and their sexual/injecting partners from the pre‐APN and APN periods, described the number/proportion of HIV cases found (positivity rate) and evaluated predictors of HIV infection among partners using logistic regression. RESULTS: Under APN 2676 PLHIV served as index cases and recruited 3735 partners for testing, compared to 4418 index cases and 2240 partners during the pre‐APN period. A total of 322 (8.6%) partners were rapid test positive during APN versus 161 (7.2%, p = 0.048) before APN. Women represented 38% of APN index cases (vs. 42% pre‐APN), 52% of partners tested (vs. 50% pre‐APN) and 56% of all PLHIV identified (vs. 63% pre‐APN). Compared to the pre‐APN period, the number of partners tested per index case recruited increased (0.5 to 1.4, p < 0.001) and the number of index cases needed to find one HIV‐positive partner decreased significantly (27.4 to 8.3, p < 0.001) under APN. CONCLUSIONS: APN was feasibly integrated within a people who inject drugs and PLHIV‐focused HIV programme, and was acceptable to high‐risk populations in Central Asia. Under APN, large numbers of sexual and injecting partners of PLHIV – including women and non‐marital partners – were tested while maintaining high positivity rates. Relative to the pre‐APN period, APN approximately tripled the number of partners recruited per index case and reduced the number of index cases needed to find a positive partner by >3 times. John Wiley and Sons Inc. 2019-07-19 /pmc/articles/PMC6639697/ /pubmed/31321890 http://dx.doi.org/10.1002/jia2.25313 Text en © 2019 The Authors. Journal of the International AIDS Society published by John Wiley & Sons Ltd on behalf of the International AIDS Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Little, Kristen M
Kan, Maxim
Samoylova, Olga
Rsaldinova, Altynai
Saliev, Daniyar
Ishokov, Faridun
Gray, Robert
Hasen, Nina S
Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia
title Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia
title_full Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia
title_fullStr Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia
title_full_unstemmed Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia
title_short Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia
title_sort implementation experiences and insights from the scale‐up of an hiv assisted partner notification intervention in central asia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639697/
https://www.ncbi.nlm.nih.gov/pubmed/31321890
http://dx.doi.org/10.1002/jia2.25313
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