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Safety and Efficacy of Palbociclib and Radiation Therapy in Patients With Metastatic Breast Cancer: Initial Results of a Novel Combination
PURPOSE: Palbociclib is a selective cyclin-dependent kinase 4/6 inhibitor approved for metastatic ER+/HER2- breast cancer. Preclinical evidence suggests a possible synergistic effect of palbociclib when combined with radiation therapy (RT); however, the toxicity of this pairing is unknown. We report...
Autores principales: | Chowdhary, Mudit, Sen, Neilayan, Chowdhary, Akansha, Usha, Lydia, Cobleigh, Melody A., Wang, Dian, Patel, Kirtesh R., Barry, Parul N., Rao, Ruta D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639750/ https://www.ncbi.nlm.nih.gov/pubmed/31360799 http://dx.doi.org/10.1016/j.adro.2019.03.011 |
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