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Human NEIL3 Gene Expression Regulated by Epigenetic-Like Oxidative DNA Modification

[Image: see text] The NEIL3 DNA repair gene is induced in cells or animal models experiencing oxidative or inflammatory stress along with oxidation of guanine (G) to 8-oxo-7,8-dihydroguanine (OG) in the genome. We hypothesize that a G-rich promoter element that is a potential G-quadruplex-forming se...

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Detalles Bibliográficos
Autores principales: Fleming, Aaron M., Zhu, Judy, Howpay Manage, Shereen A., Burrows, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640110/
https://www.ncbi.nlm.nih.gov/pubmed/31241930
http://dx.doi.org/10.1021/jacs.9b01847