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Non-lytic antibiotic treatment in community-acquired pneumococcal pneumonia does not attenuate inflammation: the PRISTINE trial

BACKGROUND: The inflammatory response in pneumococcal infection is primarily driven by immunoreactive bacterial cell wall components [lipoteichoic acid (LTA)]. An acute release of these components occurs when pneumococcal infection is treated with β-lactam antibiotics. OBJECTIVES: We hypothesized th...

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Detalles Bibliográficos
Autores principales:	Groeneveld, Geert H, van der Reyden, Tanny J, Joosten, Simone A, Bootsma, Hester J, Cobbaert, Christa M, de Vries, Jutte J C, Kuijper, Ed J, van Dissel, Jaap T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640306/ https://www.ncbi.nlm.nih.gov/pubmed/31106377 http://dx.doi.org/10.1093/jac/dkz207

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