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Hydrohalogenation of Ethynylpyridines Involving Nucleophilic Attack of a Halide Ion

[Image: see text] Efficient hydrochlorination of 2-ethynylpyridines was achieved without the use of special reagents. Ethynylpyridine readily reacts with hydrochloric acid to form a pyridinium salt. The salt formation considerably enhances the electrophilicity of the ethynyl group and attracts a chl...

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Detalles Bibliográficos
Autores principales:	Muragishi, Kengo, Asahara, Haruyasu, Nishiwaki, Nagatoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640932/ https://www.ncbi.nlm.nih.gov/pubmed/31457502 http://dx.doi.org/10.1021/acsomega.7b00133

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