Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines

[Image: see text] A palladium-catalyzed intramolecular dehydrogenative coupling reaction was developed for the synthesis of fused imidazo[1,2-a]pyrimidines and pyrazolo[1,5-a]pyrimidines. The developed protocol provides a practical approach for the synthesis of biologically important substituted pyr...

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Autores principales: Reddy Kotla, Siva K., Vandavasi, Jaya Kishore, Wang, Jeh-Jeng, Parang, Keykavous, Tiwari, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641030/
https://www.ncbi.nlm.nih.gov/pubmed/31457205
http://dx.doi.org/10.1021/acsomega.6b00417
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author Reddy Kotla, Siva K.
Vandavasi, Jaya Kishore
Wang, Jeh-Jeng
Parang, Keykavous
Tiwari, Rakesh K.
author_facet Reddy Kotla, Siva K.
Vandavasi, Jaya Kishore
Wang, Jeh-Jeng
Parang, Keykavous
Tiwari, Rakesh K.
author_sort Reddy Kotla, Siva K.
collection PubMed
description [Image: see text] A palladium-catalyzed intramolecular dehydrogenative coupling reaction was developed for the synthesis of fused imidazo[1,2-a]pyrimidines and pyrazolo[1,5-a]pyrimidines. The developed protocol provides a practical approach for the synthesis of biologically important substituted pyrimidines from easily available substrates, with a broad substrate scope under mild reaction conditions.
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spelling pubmed-66410302019-08-27 Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines Reddy Kotla, Siva K. Vandavasi, Jaya Kishore Wang, Jeh-Jeng Parang, Keykavous Tiwari, Rakesh K. ACS Omega [Image: see text] A palladium-catalyzed intramolecular dehydrogenative coupling reaction was developed for the synthesis of fused imidazo[1,2-a]pyrimidines and pyrazolo[1,5-a]pyrimidines. The developed protocol provides a practical approach for the synthesis of biologically important substituted pyrimidines from easily available substrates, with a broad substrate scope under mild reaction conditions. American Chemical Society 2017-01-04 /pmc/articles/PMC6641030/ /pubmed/31457205 http://dx.doi.org/10.1021/acsomega.6b00417 Text en Copyright © 2017 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Reddy Kotla, Siva K.
Vandavasi, Jaya Kishore
Wang, Jeh-Jeng
Parang, Keykavous
Tiwari, Rakesh K.
Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines
title Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines
title_full Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines
title_fullStr Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines
title_full_unstemmed Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines
title_short Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines
title_sort palladium-catalyzed intramolecular cross-dehydrogenative coupling: synthesis of fused imidazo[1,2-a]pyrimidines and pyrazolo[1,5-a]pyrimidines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641030/
https://www.ncbi.nlm.nih.gov/pubmed/31457205
http://dx.doi.org/10.1021/acsomega.6b00417
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