Unique Ivy-Like Morphology Composed of Poly(lactic acid) and Bacterial Cellulose Cryogel

[Image: see text] This study examines the unique morphology and properties of enhanced poly(l-lactic acid) (PLLA) monoliths having a bacterial cellulose (BC) framework. Open-porous BC/PLLA monoliths were successfully prepared using thermally induced phase separation (TIPS) and a freeze-drying technique. The BC/PLLA monoliths exhibited a unique ivy-like structure composed of leaf-like PLLA units and a BC fiber network. We demonstrated for the first time that the interpenetrating BC fiber gives PLLA monoliths four times higher compressive strength than the pristine PLLA. Scanning electron microscopy observation and the N(2) adsorption test revealed that the size of PLLA units and the surface area of the monoliths can be manipulated by varying the starting PLLA concentration during the TIPS process. Moreover, the hydrophilicity of the PLLA monoliths was easily controlled by incorporating BC; the neat PLLA monoliths showed a high static water contact angle of as high as 128.8 ± 1.1°, whereas the BC/PLLA monoliths exhibited a much lower contact angle (102.1 ± 1.7°) and greater absorbability to water.