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Diastereoselective Synthesis of Morphan Derivatives by Michael and Hetero-Michael Addition of 1,1-Enediamines to Quinone Monoketals

[Image: see text] A general and concise method was developed for the synthesis of highly functionalized morphans 3–4 by the Michael and hetero-Michael addition reaction of different types of quinone monoketals 1 and 1,1-enediamines 2 in ethanol or 1,4-dioxane at reflux. This method is suitable for t...

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Detalles Bibliográficos
Autores principales: Hu, Xing-Mei, Luo, Da-Yun, Zi, Quan-Xing, Lin, Jun, Yan, Sheng-Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641283/
https://www.ncbi.nlm.nih.gov/pubmed/31457875
http://dx.doi.org/10.1021/acsomega.7b01493