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Fast NMR Screening of Macromolecular Complexes by a Paramagnetic Spin Relaxation Filter

[Image: see text] The paramagnetic spin relaxation filter is described for the rapid NMR screening of intermolecular interactions between ligands and macromolecular anionic receptors with large transverse relaxation enhancements (R(2p)). The addition of micromolar concentrations of Gd(3+) to the mix...

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Detalles Bibliográficos
Autores principales: Pinto, Luiz F., Correa, Juan, Zhao, Libo, Riguera, Ricardo, Fernandez-Megia, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641404/
https://www.ncbi.nlm.nih.gov/pubmed/31458565
http://dx.doi.org/10.1021/acsomega.7b02074