Empowering Transition-Metal-Free Cascade Protocol for the Green Synthesis of Biaryls and Alkynes

[Image: see text] The work being presented in this paper demonstrates the simple and efficient “transition-metal-free” and “light-mediated” synthetic protocol for the synthesis of aryl iodides/biaryls/alkynes from aryl bromides. Under ultraviolet irradiation and in basic aqueous media, aryl bromides...

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Autores principales: Walia, Preet Kamal, Kumar, Manoj, Bhalla, Vandana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641525/
https://www.ncbi.nlm.nih.gov/pubmed/31458507
http://dx.doi.org/10.1021/acsomega.7b02014
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author Walia, Preet Kamal
Kumar, Manoj
Bhalla, Vandana
author_facet Walia, Preet Kamal
Kumar, Manoj
Bhalla, Vandana
author_sort Walia, Preet Kamal
collection PubMed
description [Image: see text] The work being presented in this paper demonstrates the simple and efficient “transition-metal-free” and “light-mediated” synthetic protocol for the synthesis of aryl iodides/biaryls/alkynes from aryl bromides. Under ultraviolet irradiation and in basic aqueous media, aryl bromides undergo transformation into aryl iodides which efficiently couple via a cascade reaction with a wide range of terminal alkynes/unactivated arenes to generate target molecules under green conditions.
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spelling pubmed-66415252019-08-27 Empowering Transition-Metal-Free Cascade Protocol for the Green Synthesis of Biaryls and Alkynes Walia, Preet Kamal Kumar, Manoj Bhalla, Vandana ACS Omega [Image: see text] The work being presented in this paper demonstrates the simple and efficient “transition-metal-free” and “light-mediated” synthetic protocol for the synthesis of aryl iodides/biaryls/alkynes from aryl bromides. Under ultraviolet irradiation and in basic aqueous media, aryl bromides undergo transformation into aryl iodides which efficiently couple via a cascade reaction with a wide range of terminal alkynes/unactivated arenes to generate target molecules under green conditions. American Chemical Society 2018-02-16 /pmc/articles/PMC6641525/ /pubmed/31458507 http://dx.doi.org/10.1021/acsomega.7b02014 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Walia, Preet Kamal
Kumar, Manoj
Bhalla, Vandana
Empowering Transition-Metal-Free Cascade Protocol for the Green Synthesis of Biaryls and Alkynes
title Empowering Transition-Metal-Free Cascade Protocol for the Green Synthesis of Biaryls and Alkynes
title_full Empowering Transition-Metal-Free Cascade Protocol for the Green Synthesis of Biaryls and Alkynes
title_fullStr Empowering Transition-Metal-Free Cascade Protocol for the Green Synthesis of Biaryls and Alkynes
title_full_unstemmed Empowering Transition-Metal-Free Cascade Protocol for the Green Synthesis of Biaryls and Alkynes
title_short Empowering Transition-Metal-Free Cascade Protocol for the Green Synthesis of Biaryls and Alkynes
title_sort empowering transition-metal-free cascade protocol for the green synthesis of biaryls and alkynes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641525/
https://www.ncbi.nlm.nih.gov/pubmed/31458507
http://dx.doi.org/10.1021/acsomega.7b02014
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