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Catalyst-Free Synthesis of 2,4-Disubstituted-1H-imidazoles through [3 + 2] Cyclization of Vinyl Azides with Amidines

[Image: see text] A facile and efficient route for the synthesis of 2,4-disubstituted imidazoles from benzimidamides and vinyl azides through [3 + 2] cyclization under catalyst-free conditions has been described. The method is compatible for a broad range of functional groups with good to excellent...

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Detalles Bibliográficos
Autores principales: Reddy, N. Naresh Kumar, Nageswara Rao, Sadu, Ravi, Chitrakar, Adimurthy, Subbarayappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641739/
https://www.ncbi.nlm.nih.gov/pubmed/31457795
http://dx.doi.org/10.1021/acsomega.7b00969