Iodine-Catalyzed Chemoselective Hydroamination Reaction Using 5-Mercaptotetrazoles Derivatives

[Image: see text] Metal-free chemoselective hydroamination of styrene derivatives has been achieved with high chemoselectivity over sulfenylation of 1H-tetrazole-5-thiol using a catalytic amount of iodine. The scope of this methodology has been extended for the hydroamination of α-substituted styren...

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Autores principales: Siddaraju, Yogesh, Prabhu, Kandikere Ramaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641749/
https://www.ncbi.nlm.nih.gov/pubmed/31458707
http://dx.doi.org/10.1021/acsomega.8b00499
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author Siddaraju, Yogesh
Prabhu, Kandikere Ramaiah
author_facet Siddaraju, Yogesh
Prabhu, Kandikere Ramaiah
author_sort Siddaraju, Yogesh
collection PubMed
description [Image: see text] Metal-free chemoselective hydroamination of styrene derivatives has been achieved with high chemoselectivity over sulfenylation of 1H-tetrazole-5-thiol using a catalytic amount of iodine. The scope of this methodology has been extended for the hydroamination of α-substituted styrene derivatives. This reaction involves a single-step C–N-bond formation under atom economical process. This eco-friendly method uses readily available and inexpensive iodine in a catalytic amount.
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spelling pubmed-66417492019-08-27 Iodine-Catalyzed Chemoselective Hydroamination Reaction Using 5-Mercaptotetrazoles Derivatives Siddaraju, Yogesh Prabhu, Kandikere Ramaiah ACS Omega [Image: see text] Metal-free chemoselective hydroamination of styrene derivatives has been achieved with high chemoselectivity over sulfenylation of 1H-tetrazole-5-thiol using a catalytic amount of iodine. The scope of this methodology has been extended for the hydroamination of α-substituted styrene derivatives. This reaction involves a single-step C–N-bond formation under atom economical process. This eco-friendly method uses readily available and inexpensive iodine in a catalytic amount. American Chemical Society 2018-05-04 /pmc/articles/PMC6641749/ /pubmed/31458707 http://dx.doi.org/10.1021/acsomega.8b00499 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Siddaraju, Yogesh
Prabhu, Kandikere Ramaiah
Iodine-Catalyzed Chemoselective Hydroamination Reaction Using 5-Mercaptotetrazoles Derivatives
title Iodine-Catalyzed Chemoselective Hydroamination Reaction Using 5-Mercaptotetrazoles Derivatives
title_full Iodine-Catalyzed Chemoselective Hydroamination Reaction Using 5-Mercaptotetrazoles Derivatives
title_fullStr Iodine-Catalyzed Chemoselective Hydroamination Reaction Using 5-Mercaptotetrazoles Derivatives
title_full_unstemmed Iodine-Catalyzed Chemoselective Hydroamination Reaction Using 5-Mercaptotetrazoles Derivatives
title_short Iodine-Catalyzed Chemoselective Hydroamination Reaction Using 5-Mercaptotetrazoles Derivatives
title_sort iodine-catalyzed chemoselective hydroamination reaction using 5-mercaptotetrazoles derivatives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641749/
https://www.ncbi.nlm.nih.gov/pubmed/31458707
http://dx.doi.org/10.1021/acsomega.8b00499
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AT prabhukandikereramaiah iodinecatalyzedchemoselectivehydroaminationreactionusing5mercaptotetrazolesderivatives

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