Significant association of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) rs3846662 and sirtuin 1 (SIRT1) rs7895833 and apolipoprotein E (APOE) hypermethylation with mild cognitive impairment (MCI)

Our study investigated the association of five genes with MCI in the Xinjiang Uygur population in China. In addition, we also analyzed the association between APOE methylation and MCI. Forty-three MCI and 125 controls were included in the present study. Genotyping was done by Sanger sequencing. DNA...

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Detalles Bibliográficos
Autores principales: Zou, Ting, Duan, Yali, Zhou, Xiaohui, Chen, Wei, Ying, Xiuru, Liu, Guili, Zhao, Yongjie, Zhu, Meisheng, Pari, Abuliz, Alimu, Kader, Miao, Haijun, Kabinur, Keyim, Zhang, Lei, Wang, Qinwen, Duan, Shiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641831/
https://www.ncbi.nlm.nih.gov/pubmed/31305452
http://dx.doi.org/10.1097/MD.0000000000016405

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