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Catalyst-Free Cross-Dehydrogenative Coupling Strategy Using Air as an Oxidant: Synthesis of α-Aminophosphonates
[Image: see text] α-Aminophosphonates are synthesized by employing unfunctionalized starting materials using cross-dehydrogenative coupling strategy. This method does not require any catalyst and proceeds in the presence of open air as the only oxidant. Mechanistic studies revealed that the reaction...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641911/ https://www.ncbi.nlm.nih.gov/pubmed/31457767 http://dx.doi.org/10.1021/acsomega.7b00881 |
| _version_ | 1783436882290409472 |
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| author | Dhineshkumar, Jayaraman Samaddar, Prasanjit Prabhu, Kandikere Ramaiah |
| author_facet | Dhineshkumar, Jayaraman Samaddar, Prasanjit Prabhu, Kandikere Ramaiah |
| author_sort | Dhineshkumar, Jayaraman |
| collection | PubMed |
| description | [Image: see text] α-Aminophosphonates are synthesized by employing unfunctionalized starting materials using cross-dehydrogenative coupling strategy. This method does not require any catalyst and proceeds in the presence of open air as the only oxidant. Mechanistic studies revealed that the reaction is nucleophile dependent and specific to dialkyl phosphite and N-aryl tetrahydroisoquinoline derivatives. |
| format | Online Article Text |
| id | pubmed-6641911 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | American Chemical Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-66419112019-08-27 Catalyst-Free Cross-Dehydrogenative Coupling Strategy Using Air as an Oxidant: Synthesis of α-Aminophosphonates Dhineshkumar, Jayaraman Samaddar, Prasanjit Prabhu, Kandikere Ramaiah ACS Omega [Image: see text] α-Aminophosphonates are synthesized by employing unfunctionalized starting materials using cross-dehydrogenative coupling strategy. This method does not require any catalyst and proceeds in the presence of open air as the only oxidant. Mechanistic studies revealed that the reaction is nucleophile dependent and specific to dialkyl phosphite and N-aryl tetrahydroisoquinoline derivatives. American Chemical Society 2017-08-23 /pmc/articles/PMC6641911/ /pubmed/31457767 http://dx.doi.org/10.1021/acsomega.7b00881 Text en Copyright © 2017 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes. |
| spellingShingle | Dhineshkumar, Jayaraman Samaddar, Prasanjit Prabhu, Kandikere Ramaiah Catalyst-Free Cross-Dehydrogenative Coupling Strategy Using Air as an Oxidant: Synthesis of α-Aminophosphonates |
| title | Catalyst-Free Cross-Dehydrogenative Coupling Strategy
Using Air as an Oxidant: Synthesis
of α-Aminophosphonates |
| title_full | Catalyst-Free Cross-Dehydrogenative Coupling Strategy
Using Air as an Oxidant: Synthesis
of α-Aminophosphonates |
| title_fullStr | Catalyst-Free Cross-Dehydrogenative Coupling Strategy
Using Air as an Oxidant: Synthesis
of α-Aminophosphonates |
| title_full_unstemmed | Catalyst-Free Cross-Dehydrogenative Coupling Strategy
Using Air as an Oxidant: Synthesis
of α-Aminophosphonates |
| title_short | Catalyst-Free Cross-Dehydrogenative Coupling Strategy
Using Air as an Oxidant: Synthesis
of α-Aminophosphonates |
| title_sort | catalyst-free cross-dehydrogenative coupling strategy
using air as an oxidant: synthesis
of α-aminophosphonates |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641911/ https://www.ncbi.nlm.nih.gov/pubmed/31457767 http://dx.doi.org/10.1021/acsomega.7b00881 |
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