I(2)-Catalyzed Oxidative Cross-Coupling Reaction of Methyl Ketones and 2-(2-Aminophenyl) Benzimidazole: Facile Access to Benzimidazo[1,2-c]quinazoline

[Image: see text] A general and efficient iodine-catalyzed metal-free oxidative cross-coupling reaction of methyl ketones with 2-(1H-benzo[d]imidazol-2-yl)aniline has been established. This is a new synthetic strategy for the synthesis of benzimidazo[1,2-c]quinazoline derivatives involving C(sp(3))–...

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Autores principales: Ambethkar, Sethurajan, Kalaiselvi, Mariappan, Ramamoorthy, Jaganathan, Padmini, Vediappen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641929/
https://www.ncbi.nlm.nih.gov/pubmed/31458715
http://dx.doi.org/10.1021/acsomega.8b00067
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author Ambethkar, Sethurajan
Kalaiselvi, Mariappan
Ramamoorthy, Jaganathan
Padmini, Vediappen
author_facet Ambethkar, Sethurajan
Kalaiselvi, Mariappan
Ramamoorthy, Jaganathan
Padmini, Vediappen
author_sort Ambethkar, Sethurajan
collection PubMed
description [Image: see text] A general and efficient iodine-catalyzed metal-free oxidative cross-coupling reaction of methyl ketones with 2-(1H-benzo[d]imidazol-2-yl)aniline has been established. This is a new synthetic strategy for the synthesis of benzimidazo[1,2-c]quinazoline derivatives involving C(sp(3))–H oxidation, condensation, and cyclization processes.
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spelling pubmed-66419292019-08-27 I(2)-Catalyzed Oxidative Cross-Coupling Reaction of Methyl Ketones and 2-(2-Aminophenyl) Benzimidazole: Facile Access to Benzimidazo[1,2-c]quinazoline Ambethkar, Sethurajan Kalaiselvi, Mariappan Ramamoorthy, Jaganathan Padmini, Vediappen ACS Omega [Image: see text] A general and efficient iodine-catalyzed metal-free oxidative cross-coupling reaction of methyl ketones with 2-(1H-benzo[d]imidazol-2-yl)aniline has been established. This is a new synthetic strategy for the synthesis of benzimidazo[1,2-c]quinazoline derivatives involving C(sp(3))–H oxidation, condensation, and cyclization processes. American Chemical Society 2018-05-08 /pmc/articles/PMC6641929/ /pubmed/31458715 http://dx.doi.org/10.1021/acsomega.8b00067 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Ambethkar, Sethurajan
Kalaiselvi, Mariappan
Ramamoorthy, Jaganathan
Padmini, Vediappen
I(2)-Catalyzed Oxidative Cross-Coupling Reaction of Methyl Ketones and 2-(2-Aminophenyl) Benzimidazole: Facile Access to Benzimidazo[1,2-c]quinazoline
title I(2)-Catalyzed Oxidative Cross-Coupling Reaction of Methyl Ketones and 2-(2-Aminophenyl) Benzimidazole: Facile Access to Benzimidazo[1,2-c]quinazoline
title_full I(2)-Catalyzed Oxidative Cross-Coupling Reaction of Methyl Ketones and 2-(2-Aminophenyl) Benzimidazole: Facile Access to Benzimidazo[1,2-c]quinazoline
title_fullStr I(2)-Catalyzed Oxidative Cross-Coupling Reaction of Methyl Ketones and 2-(2-Aminophenyl) Benzimidazole: Facile Access to Benzimidazo[1,2-c]quinazoline
title_full_unstemmed I(2)-Catalyzed Oxidative Cross-Coupling Reaction of Methyl Ketones and 2-(2-Aminophenyl) Benzimidazole: Facile Access to Benzimidazo[1,2-c]quinazoline
title_short I(2)-Catalyzed Oxidative Cross-Coupling Reaction of Methyl Ketones and 2-(2-Aminophenyl) Benzimidazole: Facile Access to Benzimidazo[1,2-c]quinazoline
title_sort i(2)-catalyzed oxidative cross-coupling reaction of methyl ketones and 2-(2-aminophenyl) benzimidazole: facile access to benzimidazo[1,2-c]quinazoline
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641929/
https://www.ncbi.nlm.nih.gov/pubmed/31458715
http://dx.doi.org/10.1021/acsomega.8b00067
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