Efficient New Protocols for Converting Primary Amides into Nitriles Initiated by P(NMe(2))(3), PCl(3), or P(OPh)(3)

[Image: see text] Three efficient and high-yielding procedures have been developed for the conversion of primary amides into nitriles, mediated by hitherto unexplored P(NMe(2))(3), PCl(3), or P(OPh)(3). The reactions were conducted under operationally simple and mild conditions and displayed broad s...

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Autores principales: Talbi, Imen, Efrit, Mohamed Lotfi, Touil, Soufiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641971/
https://www.ncbi.nlm.nih.gov/pubmed/31458722
http://dx.doi.org/10.1021/acsomega.8b00544
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author Talbi, Imen
Efrit, Mohamed Lotfi
Touil, Soufiane
author_facet Talbi, Imen
Efrit, Mohamed Lotfi
Touil, Soufiane
author_sort Talbi, Imen
collection PubMed
description [Image: see text] Three efficient and high-yielding procedures have been developed for the conversion of primary amides into nitriles, mediated by hitherto unexplored P(NMe(2))(3), PCl(3), or P(OPh)(3). The reactions were conducted under operationally simple and mild conditions and displayed broad substrate scope and good functional group tolerance.
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spelling pubmed-66419712019-08-27 Efficient New Protocols for Converting Primary Amides into Nitriles Initiated by P(NMe(2))(3), PCl(3), or P(OPh)(3) Talbi, Imen Efrit, Mohamed Lotfi Touil, Soufiane ACS Omega [Image: see text] Three efficient and high-yielding procedures have been developed for the conversion of primary amides into nitriles, mediated by hitherto unexplored P(NMe(2))(3), PCl(3), or P(OPh)(3). The reactions were conducted under operationally simple and mild conditions and displayed broad substrate scope and good functional group tolerance. American Chemical Society 2018-05-09 /pmc/articles/PMC6641971/ /pubmed/31458722 http://dx.doi.org/10.1021/acsomega.8b00544 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Talbi, Imen
Efrit, Mohamed Lotfi
Touil, Soufiane
Efficient New Protocols for Converting Primary Amides into Nitriles Initiated by P(NMe(2))(3), PCl(3), or P(OPh)(3)
title Efficient New Protocols for Converting Primary Amides into Nitriles Initiated by P(NMe(2))(3), PCl(3), or P(OPh)(3)
title_full Efficient New Protocols for Converting Primary Amides into Nitriles Initiated by P(NMe(2))(3), PCl(3), or P(OPh)(3)
title_fullStr Efficient New Protocols for Converting Primary Amides into Nitriles Initiated by P(NMe(2))(3), PCl(3), or P(OPh)(3)
title_full_unstemmed Efficient New Protocols for Converting Primary Amides into Nitriles Initiated by P(NMe(2))(3), PCl(3), or P(OPh)(3)
title_short Efficient New Protocols for Converting Primary Amides into Nitriles Initiated by P(NMe(2))(3), PCl(3), or P(OPh)(3)
title_sort efficient new protocols for converting primary amides into nitriles initiated by p(nme(2))(3), pcl(3), or p(oph)(3)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641971/
https://www.ncbi.nlm.nih.gov/pubmed/31458722
http://dx.doi.org/10.1021/acsomega.8b00544
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