Biosynthetic homeostasis and resilience of the complement system in health and infectious disease

BACKGROUND: The complement system is a central component of the innate immune system. Constitutive biosynthesis of complement proteins is essential for homeostasis. Dysregulation as a consequence of genetic or environmental cues can lead to inflammatory syndromes or increased susceptibility to infec...

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Detalles Bibliográficos
Autores principales: Willems, Esther, Alkema, Wynand, Keizer-Garritsen, Jenneke, Suppers, Anouk, van der Flier, Michiel, Philipsen, Ria H.L.A., van den Heuvel, Lambert P., Volokhina, Elena, van der Molen, Renate G., Herberg, Jethro A., Levin, Michael, Wright, Victoria J., Ahout, Inge M.L., Ferwerda, Gerben, Emonts, Marieke, Boeddha, Navin P., Rivero-Calle, Irene, Torres, Federico Martinon, Wessels, Hans J.C.T., de Groot, Ronald, van Gool, Alain J., Gloerich, Jolein, de Jonge, Marien I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642076/
https://www.ncbi.nlm.nih.gov/pubmed/31262714
http://dx.doi.org/10.1016/j.ebiom.2019.06.008

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