A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses

Aneuploidy has been reported to occur at remarkably high levels in normal somatic tissues using Fluorescence In Situ Hybridization (FISH). Recently, these reports were contradicted by single-cell low-coverage whole genome sequencing (scL-WGS) analyses, which showed aneuploidy frequencies at least an...

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Detalles Bibliográficos
Autores principales: Andriani, Grasiella A., Maggi, Elaine, Piqué, Daniel, Zimmerman, Samuel E., Lee, Moonsook, Quispe-Tintaya, Wilber, Maslov, Alexander, Campisi, Judith, Vijg, Jan, Mar, Jessica C., Montagna, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642082/
https://www.ncbi.nlm.nih.gov/pubmed/31324840
http://dx.doi.org/10.1038/s41598-019-46606-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642082/
https://www.ncbi.nlm.nih.gov/pubmed/31324840
http://dx.doi.org/10.1038/s41598-019-46606-w

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