Alternative splicing regulates stochastic NLRP3 activity

Leucine-rich repeat (LRR) domains are evolutionarily conserved in proteins that function in development and immunity. Here we report strict exonic modularity of LRR domains of several human gene families, which is a precondition for alternative splicing (AS). We provide evidence for AS of LRR domain...

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Detalles Bibliográficos
Autores principales: Hoss, Florian, Mueller, James L., Rojas Ringeling, Francisca, Rodriguez-Alcazar, Juan F., Brinkschulte, Rebecca, Seifert, Gerald, Stahl, Rainer, Broderick, Lori, Putnam, Chris D., Kolodner, Richard D., Canzar, Stefan, Geyer, Matthias, Hoffman, Hal M., Latz, Eicke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642158/
https://www.ncbi.nlm.nih.gov/pubmed/31324763
http://dx.doi.org/10.1038/s41467-019-11076-1

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