Cargando…
A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours
Accumulating evidence indicates that the zinc-finger transcription factor ZEB1 is predominantly expressed in the stroma of several tumours. However, the role of stromal ZEB1 in tumour progression remains unexplored. In this study, while interrogating human databases, we uncover a remarkable decrease...
Autores principales: | Fu, Rong, Han, Chen-Feng, Ni, Ting, Di, Lei, Liu, Li-Juan, Lv, Wen-Cong, Bi, Yan-Ran, Jiang, Nan, He, Yin, Li, Hong-Mei, Wang, Shui, Xie, Hui, Chen, Bao-An, Wang, Xiao-Sheng, Weiss, Stephen J., Lu, Tao, Guo, Qing-Long, Wu, Zhao-Qiu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642263/ https://www.ncbi.nlm.nih.gov/pubmed/31324807 http://dx.doi.org/10.1038/s41467-019-11278-7 |
Ejemplares similares
-
Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer
por: Galván, J A, et al.
Publicado: (2015) -
Pten in Stromal Fibroblasts Suppresses Mammary Epithelial Tumors
por: Trimboli, Anthony J., et al.
Publicado: (2009) -
Stromal accumulation of chondroitin sulphate in mammary tumours of dogs
por: Hinrichs, U, et al.
Publicado: (1999) -
Tumour-stromal interactions: Role of the stroma in mammary development
por: Silberstein, Gary B
Publicado: (2001) -
Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis
por: Rudnick, Jenny A., et al.
Publicado: (2021)