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Translational assessment of a genetic engineering methodology to improve islet function for transplantation

BACKGROUND: The functional quality of insulin-secreting islet beta cells is a major factor determining the outcome of clinical transplantations for diabetes. It is therefore of importance to develop methodological strategies aiming at optimizing islet cell function prior to transplantation. In this...

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Detalles Bibliográficos
Autores principales: van Krieken, Pim P., Voznesenskaya, Anna, Dicker, Andrea, Xiong, Yan, Park, Jae Hong, Lee, Jeong Ik, Ilegems, Erwin, Berggren, Per-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642289/
https://www.ncbi.nlm.nih.gov/pubmed/31262716
http://dx.doi.org/10.1016/j.ebiom.2019.06.045