Cargando…

TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer

BACKGROUND: Tumour necrosis factor receptor associated factor 6 (TRAF6) promotes inflammation in response to various cytokines. Aberrant Wnt3a signals promotes cancer progression through accumulation of β-Catenin. Here we investigated a potential role for TRAF6 in Wnt signaling. METHODS: TRAF6 expre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aripaka, Karthik, Gudey, Shyam Kumar, Zang, Guangxiang, Schmidt, Alexej, Åhrling, Samaneh Shabani, Österman, Lennart, Bergh, Anders, von Hofsten, Jonas, Landström, Marene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642315/ https://www.ncbi.nlm.nih.gov/pubmed/31262711 http://dx.doi.org/10.1016/j.ebiom.2019.06.046

Ejemplares similares

TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor
por: Sundar, Reshma, et al.
Publicado: (2015)

Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer
por: Gudey, Shyam Kumar, et al.
Publicado: (2017)

PKCζ facilitates lymphatic metastatic spread of prostate cancer cells in a mice xenograft model
por: Zang, Guangxiang, et al.
Publicado: (2019)

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1
por: Thakur, Noopur, et al.
Publicado: (2014)

Interactions between TGF-β type I receptor and hypoxia-inducible factor-α mediates a synergistic crosstalk leading to poor prognosis for patients with clear cell renal cell carcinoma
por: Mallikarjuna, Pramod, et al.
Publicado: (2019)

TGFβ activates PI3K-AKT signaling via TRAF6
por: Song, Jie, et al.
Publicado: (2017)

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer
por: Mu, Yabing, et al.
Publicado: (2011)

CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface
por: Yakymovych, Ihor, et al.
Publicado: (2015)

The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
por: Song, Jie, et al.
Publicado: (2022)

Combined Transcriptomic and Protein Array Cytokine Profiling of Human Stem Cells from Dental Apical Papilla Modulated by Oral Bacteria
por: Zymovets, Valeriia, et al.
Publicado: (2022)

Cytokine Secretion, Viability, and Real-Time Proliferation of Apical-Papilla Stem Cells Upon Exposure to Oral Bacteria
por: Rakhimova, Olena, et al.
Publicado: (2021)

Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells
por: Thakur, Noopur, et al.
Publicado: (2020)

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain
por: Song, Jie, et al.
Publicado: (2015)

Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein
por: Davoodpour, Padideh, et al.
Publicado: (2007)

The 2019 FASEB Science Research Conference on the TGF-β Superfamily: Signaling in Development and Disease, July 28 to August 2, 2019, West Palm Beach, Florida, USA
por: Landström, Marene, et al.
Publicado: (2019)

The Synergistic Cooperation between TGF-β and Hypoxia in Cancer and Fibrosis
por: Mallikarjuna, Pramod, et al.
Publicado: (2022)

Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma
por: Sitaram, Raviprakash T., et al.
Publicado: (2016)

VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma
por: Mallikarjuna, Pramod, et al.
Publicado: (2018)

Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adhesion molecules
por: Hollandsworth, Hannah M., et al.
Publicado: (2020)

Comparison of Target Recognition by TRAF1 and TRAF2
por: Kim, Chang Min, et al.
Publicado: (2020)

Zebrafish sex determination and differentiation: Involvement of FTZ-F1 genes
por: von Hofsten, Jonas, et al.
Publicado: (2005)

Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway
por: Kim, Chang Min, et al.
Publicado: (2016)

Different Activation of TRAF4 and TRAF6 in Inflammatory Bowel Disease
por: Shen, Jun, et al.
Publicado: (2013)

Regulation of the Subcellular Localization of Tumor Necrosis Factor Receptor–associated Factor (TRAF)2 by TRAF1 Reveals Mechanisms of TRAF2 Signaling
por: Arron, Joseph R., et al.
Publicado: (2002)

A Balance of BMP and Notch Activity Regulates Neurogenesis and Olfactory Nerve Formation
por: Maier, Esther, et al.
Publicado: (2011)

The zebrafish HGF receptor met controls migration of myogenic progenitor cells in appendicular development
por: Nord, Hanna, et al.
Publicado: (2019)

Pax7 is required for establishment of the xanthophore lineage in zebrafish embryos
por: Nord, Hanna, et al.
Publicado: (2016)

Up-regulation and Pre-activation of TRAF3 and TRAF5 in Inflammatory Bowel Disease
por: Shen, Jun, et al.
Publicado: (2013)

Prognostic Significance of TNFR-Associated Factor 1 and 2 (TRAF1 and TRAF2) in Glioblastoma
por: Zhang, Wenqing, et al.
Publicado: (2017)

Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?
por: Petrova, Tsvetana, et al.
Publicado: (2022)

Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction
por: Xie, Xiaoping, et al.
Publicado: (2019)

Brief Research Report Regional Difference in TRAF2 and TRAF3 Gene Mutations in Colon Cancers
por: Moon, Seong Won, et al.
Publicado: (2021)

Single-cell DNA sequencing reveals order of mutational acquisition in TRAF7/AKT1 and TRAF7/KLF4 mutant meningiomas
por: Dogan, Helin, et al.
Publicado: (2022)

Editorial: TRAF Proteins in Health and Disease
por: Bishop, Gail A., et al.
Publicado: (2019)

The relationship between TRAF6 and tumors
por: Li, Jiaoduan, et al.
Publicado: (2020)

Roles of TRAFs in Ischemia-Reperfusion Injury
por: Zhou, Wei, et al.
Publicado: (2020)

TRAF2 Mediates Physiological Mitophagy
por: Sadoshima, Junichi
Publicado: (2022)

TRAF3: Guardian of T lymphocyte functions
por: Hornick, Emma L., et al.
Publicado: (2023)

The Roles of TRAF3 in Immune Responses
por: Lin, Mengjiao, et al.
Publicado: (2023)

TRAF-STOP alleviates osteoclastogenesis in periodontitis
por: Huang, Yaxian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8b8mfve6n4mjhvet4m2b8gan26