Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells

BACKGROUND: Bone metastases are common and devastating to cancer patients. Existing treatments do not specifically target the disease sites and are therefore ineffective and systemically toxic. Here we present a new strategy to treat bone metastasis by targeting both the cancer cells (“the seed”), a...

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Detalles Bibliográficos
Autores principales: Segaliny, Aude I., Cheng, Jason L., Farhoodi, Henry P., Toledano, Michael, Yu, Chih Chun, Tierra, Beatrice, Hildebrand, Leanne, Liu, Linan, Liao, Michael J., Cho, Jaedu, Liu, Dongxu, Sun, Lizhi, Gulsen, Gultekin, Su, Min-Ying, Sah, Robert L., Zhao, Weian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642316/
https://www.ncbi.nlm.nih.gov/pubmed/31281099
http://dx.doi.org/10.1016/j.ebiom.2019.06.047

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