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Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma

BACKGROUND: Abnormal construction of the extracellular matrix (ECM) is intimately linked with carcinogenesis and the development of solid tumours, especially hepatocellular carcinoma (HCC). As the major component of the ECM, collagen plays a pivotal role in carcinogenesis. P4HA2, the essential enzym...

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Detalles Bibliográficos
Autores principales:	Wang, Tianjiao, Fu, Xueli, Jin, Tianzhi, Zhang, Lu, Liu, Bowen, Wu, Yue, Xu, Feifei, Wang, Xue, Ye, Kai, Zhang, Weiying, Ye, Lihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642319/ https://www.ncbi.nlm.nih.gov/pubmed/31278071 http://dx.doi.org/10.1016/j.ebiom.2019.06.048

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